diff --git a/src/tests/JIT/opt/GuardedDevirtualization/badinlinee.csproj b/src/tests/JIT/opt/GuardedDevirtualization/badinlinee.csproj
index 5d2eec4b7dbfae..cf9f2e0fccd5ca 100644
--- a/src/tests/JIT/opt/GuardedDevirtualization/badinlinee.csproj
+++ b/src/tests/JIT/opt/GuardedDevirtualization/badinlinee.csproj
@@ -3,6 +3,10 @@
     <CLRTestPriority>1</CLRTestPriority>
     <Optimize>True</Optimize>
     <RequiresProcessIsolation>true</RequiresProcessIsolation>
+    <!-- ActiveIssue https://github.com/dotnet/runtime/issues/134169 -->
+    <CLRTestTargetUnsupported Condition="'$(RuntimeFlavor)' == 'coreclr' and '$(TargetOS)' == 'browser'">true</CLRTestTargetUnsupported>
+    <!-- Tiered compilation is disabled in interpreter mode. -->
+    <InterpreterIncompatible>true</InterpreterIncompatible>
   </PropertyGroup>
   <ItemGroup>
     <Compile Include="$(MSBuildProjectName).cs" />