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@How-to-Learn-to-Code @ToxPi

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daynefiler/README.md

I build robust, maintainable software and reproducible analytical systems for research and data-intensive organizations. My work spans R package development, scientific pipelines, statistical computing, bioinformatics, simulation, visualization, databases, and technical training.

My background combines an MD and PhD in Bioinformatics and Computational Biology with several years of computational toxicology research at the U.S. EPA. I have also designed and taught graduate-level R programming courses and have worked across academic, clinical laboratory, government, and industry settings.

I am available for hourly consulting, fixed-scope projects, code review, and short-term contract work in research software, scientific computing, statistics, bioinformatics, and reproducible research.

Selected work

  • tcpl — R package and SQL-backed analytical infrastructure for high-throughput chemical screening data.
  • toxpiR — scientific decision-analysis software implementing the Toxicological Priority Index framework in R.
  • filer2020A — a scientific publication distributed as a reproducible R package.
  • How to Learn to Code / Practical R — graduate-level R programming curriculum for scientific researchers.

Areas I work in

  • R software and package development
  • Reproducible analytic pipelines
  • Statistical and scientific computing
  • Bioinformatics and genomics
  • Shiny applications and analytical tools
  • Legacy R code rescue, refactoring, testing, and documentation
  • Scientific communication and technical training

For performance-critical R software, I also work with C, C++, and Fortran interfaces. For larger workflows, I use tools including targets, renv, Snakemake, conda, SQL, Linux/Bash, Quarto/R Markdown, and the broader Posit ecosystem.

Links

Pinned Loading

  1. ToxPi/toxpiR ToxPi/toxpiR Public

    toxpiR R package for the Toxicological Priority Index (ToxPi) algorithm.

    R 11 5

  2. USEPA/CompTox-ToxCast-tcpl USEPA/CompTox-ToxCast-tcpl Public

    US EPA's Toxicity Forecaster (ToxCast) Pipeline. More information on the ToxCast program available here: https://www.epa.gov/comptox-tools/toxicity-forecasting-toxcast

    R 46 21

  3. filer2020A filer2020A Public

    TeX

  4. mcCNV mcCNV Public

    R package for estimating copy-number variation from targeted DNA sequencing

    R

  5. gnomadR gnomadR Public

    R package to access gnomAD API (under development)

    R 3 4

  6. emanuelealiverti/BC_tSNE emanuelealiverti/BC_tSNE Public

    Batch-corrected t-SNE

    C 6 1