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@inDEPTHlab

inDEPTH lab

Research group at Erasmus MC. Our goal is to understand how genetic and environmental influences shape children’s development, behaviour and mental health.

Repository for inDEPTHlab research

This repository contains contains code used in research conducted by the inDEPTHlab. Most scripts are specific to the Generation R study, but some packages and scripts could be useful to the wider molecular epidemiology community.

Study repositories

omicsR2

Neumann, A., Pingault, JB., Felix, J.F. et al. Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach. Clin Epigenet 14, 53 (2022). https://doi.org/10.1186/s13148-022-01268-w

Epigenetic Timing Effects

Neumann, A., Sammallahti, S., Cosin-Tomas, M., Reese, S. E., Suderman, M., Alemany, S., ... & Cecil, C. (2024). Epigenetic timing effects on child developmental outcomes: A longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium. medRxiv, 2024-02. https://doi.org/10.1101/2024.02.29.24303506

Member repositories

Alexander Neumann

Serena Defina

Rosa Mulder

Tim Finke

Isabel Schuurmans

Anna Suleri

Charlotte Cecil

Popular repositories Loading

  1. GenR-run-GWAS GenR-run-GWAS Public

    Hi, this is a quick guide to running a GWAS using Generation R data.

    Shell 2 1

  2. imputation imputation Public

    Documents to help handle missing data

    R 1

  3. epigenetics epigenetics Public

    Useful information for DNA methylation and miRNA data in Generation R.

    R 1

  4. indepth indepth Public

    Loose collection of R functions useful for genetic and epigenetic analyses.

    R

  5. PRS PRS Public

    Useful scripts to generate poly(epig-)genetic risk scores.

    HTML

  6. .github .github Public

Repositories

Showing 10 of 11 repositories

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